文章摘要
刘秀,乔静敏,秦英军,岳伟平,赵志刚,尚双建,张力双.生酮饮食及限能平衡饮食对超重2型糖尿病患者身体状况的影响[J].中国临床保健杂志,2020,23(6):823-826.
生酮饮食及限能平衡饮食对超重2型糖尿病患者身体状况的影响
Effects of ketogenic diet and energy-limiting balanced diet on body composition,blood glucose,and lipids in overweight T2DM patients
投稿时间:2020-02-18  
DOI:10.3969/J.issn.1672-6790.2020.06.025
中文关键词: 糖尿病,2型  超重  膳食,减重  膳食,生酮  热量限制  身体成分  血糖  体脂
英文关键词: Diabetes mellitus,type 2  Overweight  Diet,reducing  Diet,ketogenic  Caloric restriction  Body composition  Blood glucose  Body fat 〖FL
基金项目:河北省医学科学研究重点课题(20191737);河北省石家庄市科学技术研究与发展计划项目(181460923)
作者单位E-mail
刘秀 河北石家庄市人民医院,内分泌科二病区,石家庄 050011 mingshi8848@163.com 
乔静敏 河北石家庄市人民医院,内分泌科二病区,石家庄 050011  
秦英军 河北石家庄市人民医院检验科,石家庄 050011  
岳伟平 河北石家庄市人民医院,内分泌科二病区,石家庄 050011  
赵志刚 河北石家庄市人民医院,内分泌科二病区,石家庄 050011  
尚双建 河北石家庄市人民医院心脏外科,石家庄 050011  
张力双 河北石家庄市人民医院,内分泌科二病区,石家庄 050011 2803912148@qq.com 
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中文摘要:
      目的 探讨生酮饮食及限能平衡饮食对超重2型糖尿病(T2DM)患者身体状况的影响。方法 选取超重T2DM患者98例,按照随机数字表法分为研究组和对照组各49例,研究组给予生酮饮食,对照组给予限能平衡饮食。比较两组干预前后的人体成分及血糖、血脂变化。结果 干预1个月后两组空腹血糖(FBG)、餐后2 h血糖(2hPG)、糖化血红蛋白(HbA1c)水平均降低,且研究组FBG、2hPG、FBG、HbA1c水平明显低于对照组,差异均有统计学意义(P<0.05);两组干预后三酰甘油(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)水平下降(P<0.05),高密度脂蛋白胆固醇(HDL-C)水平上升(P<0.05),且研究组TG、TC、LDL-C水平明显低于对照组(P<0.05),HDL-C水平明显高于对照组(P<0.05)。干预后研究组的体质量、脂肪量、肌肉量明显下降,且研究组明显低于对照组(P<0.05)。结论 生酮饮食及限能平衡饮食均可改善血糖、血脂水平,生酮饮食改善血糖水平更加明显,且生酮饮食降体质量、脂肪效果更佳,但肌肉量下降却较为严重。
英文摘要:
      Objective To explore the effects of ketogenic diet and energy-limiting balanced diet on body composition,blood glucose and lipids in patients with overweight type 2 diabetes (T2DM).Methods 98 cases of overweight T2DM patients were selected and divided into a study group and a control group with 49 cases each according to the random number table method.The study group was given a ketogenic diet and the control group was given a limited-energy balanced diet.Changes in body composition,blood glucose,and lipids before and after the intervention were compared between the two groups.Results After intervention for one month,the fasting blood glucose (FBG),2 h postprandial blood glucose (2hPG),and glycated hemoglobin (HbA1c) levels of the two groups decreased,and the levels of FBG,2hPG,FBG,and HbA1c in the study group were significantly lower than those in the control group (P<0.05);after intervention,the levels of triglyceride (TG),total cholesterol (TC),low-density lipoprotein cholesterol (LDL-C) decreased (P<0.05),and the level of high-density lipoprotein cholesterol (HDL-C) increased (P<0.05),and the levels of TG,TC,LDL-C in the study group were significantly lower than those in the control group (P<0.05),and the levels of HDL-C were significantly higher than that in the control group (P<0.05).After intervention,the body weight,fat mass and muscle mass of the study group decreased significantly,and the study group was significantly lower than that of the control group (P<0.05).Conclusion Both a ketogenic diet and a limited-energy balanced diet can improve blood lipid levels;a ketogenic diet can improve blood sugar levels,has better effects in reducing weight and fat,but the muscle mass decline is more serious.
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