文章摘要
张伟民,陈谨献,陈豪,邬义强.琥珀酸美托洛尔联合胺碘酮对心律失常患者心功能及生活质量评分的影响[J].中国临床保健杂志,2020,23(2):233-235.
琥珀酸美托洛尔联合胺碘酮对心律失常患者心功能及生活质量评分的影响
The effect of metoprolol succinate combined with amiodarone on cardiac function and QOL in patients with arrhythmia
投稿时间:2019-04-17  
DOI:10.3969/J.issn.1672-6790.2020.02.024
中文关键词: 心律失常,心性  美托洛尔  胺碘酮  生活质量
英文关键词: Arrhythmias,cardiac  Metoprolol  Amiodarone  Quality of life 〖FL
基金项目:
作者单位E-mail
张伟民 中国人民解放军联勤保障部队第九〇七医院心血管内科,南平 350000 zhanglu368558@163.com 
陈谨献 陆军厦门特勤鼓浪屿疗养中心一科  
陈豪 中国人民解放军联勤保障部队第九〇七医院心血管内科,南平 350000  
邬义强 中国人民解放军联勤保障部队第九〇七医院心血管内科,南平 350000  
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中文摘要:
      目的 探讨琥珀酸美托洛尔联合胺碘酮对心律失常患者心功能及生活质量评分(QOL)评分的影响。方法 选取96例心律失常患者,按照治疗方式的不同分为两组。对照组患者应用胺碘酮进行治疗,研究组患者在对照组的基础上联合琥珀酸美托洛尔进行治疗。观察两组患者的治疗效果、药物不良反应、QOL以及心功能的差异。结果 研究组患者QT期间以及QT离散度(QTd)明显高于对照组(P<0.05);研究组不良反应的发生率明显低于对照组(P<0.05);QOL方面研究组患者的生活质量评分明显高于对照组患者(P<0.05);心功能指标方面,研究组患者左心室射血最大分数比例、左心室舒张极限内径长度以及左心室收缩末期内径长度明显优于对照组患者(P<0.05)。结论 应用琥珀酸美托洛尔联合胺碘酮对心律失常患者进行治疗,能够明显改善患者的心功能且安全性较高。
英文摘要:
      Objective To investigate the effects of metoprolol succinate combined with amiodarone on cardiac function and QOL score in patients with arrhythmia.Methods A total of 96 patients with arrhythmia were divided into two groups according to different treatment methods.The patients in the control group were treated with amiodarone,and the patients in the study group were treated with metoprolol succinate on the basis of the control group.The therapeutic effect,adverse drug reaction,quality of life score (QOL) and cardiac function were observed.Results During QT and QTd,the patients in the study group were significantly higher than those in the control group (P<0.05),but not in the study group.The incidence of good reaction was significantly lower in the study group than in the control group (P<0.05).The QOL score of the study group was significantly higher than that of the control group (P<0.05).In terms of cardiac function,LVEF,LVES and LVEDD in the study group were significantly better than those in the control group (P<0.05).Conclusion Metoprolol succinate combined with amiodarone in the treatment of patients with heart arrhythmia can obviously improve the cardiac function index with better safety.
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