文章摘要
张应魏,贝宁,陈元春,张润泽,游丽.轻度脑桥梗死后早期神经功能缺损的影响因素分析[J].中国临床保健杂志,2020,23(2):206-209.
轻度脑桥梗死后早期神经功能缺损的影响因素分析
Analysis on the influencing factors of early neurological deficit after mild pontine infarction
投稿时间:2019-11-19  
DOI:10.3969/J.issn.1672-6790.2020.02.016
中文关键词: 脑梗死  脑桥  神经病学表现  危险因素
英文关键词: Brain infarction  Pons  Neurologic manifestations  Risk factors 〖FL
基金项目:海南省自然科学基金面上项目(818MS163)
作者单位E-mail
张应魏 海南省干部疗养院海南省老年病医院内科,海口 571100 zyyy69369@163.com 
贝宁 海南省干部疗养院海南省老年病医院内科,海口 571100  
陈元春 海南省干部疗养院海南省老年病医院内科,海口 571100  
张润泽 海南省干部疗养院海南省老年病医院内科,海口 571100  
游丽 海南省干部疗养院海南省老年病医院内科,海口 571100  
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中文摘要:
      目的 探讨轻度脑桥梗死后早期神经功能缺损的影响因素。方法 选择121例轻型脑桥梗死患者为研究对象,根据美国国立卫生研究院卒中量表(NIHSS)评分分为神经功能恶化组(41例)和神经功能非恶化组(80例),回顾性收集、比较两组患者一般资料、实验室检查及影像学相关资料结果,并进行logistic回归分析。结果 两组患者间糖尿病史、空腹血糖、出院时NIHSS评分、梗死部位、梗死灶分布、梗死层面最大直径、基底动脉狭窄、脑室旁脑白质高信号(WMH)及皮质下WMH差异有统计学意义(P<0.05)。logistic回归分析显示,脑桥下部梗死、累及脑桥腹侧表面梗死、基底动脉狭窄≥50%、脑室旁重度WMH、皮质下重度WMH为神经功能恶化的独立影响因素(P<0.05)。结论 脑桥下部梗死、累底脑桥腹侧表面梗死、基底动脉狭窄≥50%、脑室旁重度WMH、皮质下重度WMH为轻度脑桥梗死患者神经功能恶化的独立影响因素。
英文摘要:
      Objective To analyze the factors of early neurological deficit after mild pontine infarction.Methods A total of 121 patients who underwent mild pontine infarction were selected and divided into the neurodegenerative group (n=41) and the non-malignant neurologic group (n=80) according to the score of the national institutes of health stroke scale (NIHSS).The general data,laboratory examination and imaging data of two groups were collected and compared retrospectively.In addition,logistic regression analysis was performed based on this information.Results Statistical difference was found in the history of diabetes mellitus,fasting blood glucose,score of NIHSS at discharge,location of infarction,distribution of infarction focus,maximum diameter of infarction plane,stenosis of base artery,paraventricular white matter hyperintense (WMH) and subcortical WMH between two groups.According to the results of logistic regression analysis,inferior pontine infarction,accumulative infarction on the ventral surface of pontine,basilar artery stenosis ≥50%,severe paraventricular WMH,subcortical severe WMH were independent factors of neurological deterioration (P<0.05).Conclusion Inferior pontine infarction,accumulative infarction on the ventral surface of pontine,basilar artery stenosis ≥50%,severe paraventricular WMH and subcortical severe WMH are independent factors of neurological deterioration in patients with mild pontine infarction.
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