文章摘要
于楠,王佳贺.科学认识和面对长期口服药物的营养风险[J].中国临床保健杂志,2019,22(6):734-737.
科学认识和面对长期口服药物的营养风险
Scientific understanding of the nutritional risks of long-term oral drugs
投稿时间:2019-08-05  
DOI:10.3969/J.issn.1672-6790.2019.06.004
中文关键词: 营养不良  药物相关性副作用和不良反应  投药,口服  健康知识,态度,实践  健康教育
英文关键词: Malnutrition  Drug-related side effects and adverse reactions  Administration,oral  Health knowledge,attitudes,practice  Health education 〖FL
基金项目:国家重点研发计划(2018YFC2002104,SQ2018YFC200066)
作者单位E-mail
于楠 中国医科大学附属盛京医院老年病科,沈阳 110004 m13390585952_1@163.com 
王佳贺 中国医科大学附属盛京医院老年病科,沈阳 110004 wangjhcmusj@163.com 
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中文摘要:
      长期应用口服药物对患者带来的危害中除了肝肾功能损害以外,对患者营养状态的影响也较常见。近年来,有关口服药物造成患者营养不良的研究主要围绕口服降糖药物、激素以及非甾体类抗炎药物进行。二甲双胍和阿卡波糖会导致糖尿病患者体质量下降,同时,二甲双胍还会造成维生素B12吸收不良,引起患者巨幼细胞性贫血和肠道功能紊乱等。甲状腺激素治疗会引起患者骨骼和心血管系统的副作用和营养不良。非甾体抗炎药物会引起机体的胃肠道反应、肝脏损伤,进一步影响老年人的营养状态。
英文摘要:
      The long-term use of oral drug may cause the damage of liver and kidney functions of patients.Besides,the impact on the nutritional status of patients is also common.In recent years,the research on malnutrition caused by oral drugs mainly focuses on oral hypoglycemic drugs,hormones and non-steroidal anti-inflammatory drugs.Metformin and acarbose can lead to weight loss in patients with diabetes.At the same time,metformin can also cause poor absorption of vitamin B12,leading to megaloblastic anemia and intestinal dysfunction.Thyroid hormone therapy also may cause some side effects on bones and cardiovascular system and malnutrition of patients.Non-steroidal anti-inflammatory drugs can cause gastrointestinal reactions and liver damage and further affect the nutritional status of the elderly.
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