文章摘要
张涛,周利民,刘向前.吸烟对冠心病患者冠状动脉血清中硫化氢的影响[J].中国临床保健杂志,2019,22(5):631-633.
吸烟对冠心病患者冠状动脉血清中硫化氢的影响
Effect of smoking on serum hydrogen sulfide in coronary artery of patients with coronary heart disease
投稿时间:2019-03-27  
DOI:10.3969/J.issn.1672-6790.2019.05.015
中文关键词: 冠心病  硫化氢  冠状动脉疾病  吸烟
英文关键词: Coronary Disease  Hydrogen Sulfide  Coronary artery disease  Smoking〖FL
基金项目:
作者单位E-mail
张涛 安徽滁州市第一人民医院心内科,239000 273662870@qq.com 
周利民 安徽滁州市第一人民医院心内科,239000  
刘向前 安徽滁州市第一人民医院心内科,239000  
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中文摘要:
      目的 探讨吸烟对冠心病患者冠状动脉血清中硫化氢(H2S)的影响。方法 选取90例冠脉造影患者,冠状动脉造影检查正常不吸烟患者30例作为对照组,冠状动脉血管中度狭窄病变且吸烟2年以上和不吸烟患者各30例,采用敏感硫电极法测定各组冠状动脉血清中H2S浓度。结果 冠心病吸烟组和不吸烟组冠状动脉血清中H2S[(16.58±3.05)μmol/L,(30.66±3.66)μmol/L]均低于对照组[(47.98±4.89)μmol/L],P<0.05;冠心病吸烟组冠状动脉血清中H2S低于不吸烟组(P<0.05)。结论 吸烟可明显降低冠心病冠状动脉血清中H2S浓度,与冠状动脉粥样硬化具有相关性。
英文摘要:
      Objective To observe the effect of smoking on hydrogen sulfide (H2S) in coronary artery of coronary heart disease.Methods Ninety patients with coronary angiography and 30 non-smokers with normal coronary artery results were selected as control group,with moderate coronary artery stenosis and 30 cases of smoked patients for more than 2 years and non smoking patients.The concentration of H2S in coronary blood serum was measured by sensitive sulfur electrode.Results The serum levels of H2S in coronary blood serum of smoking group and non smoking group were lower than those of control group (P<0.05),H2S in coronary artery serum of coronary heart disease group was lower than that of non smoking group (P<0.05).Conclusion Smoking can significantly reduce the coronary artery serum H2S in patients with coronary heart disease,and is associated with coronary atherosclerosis.
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