文章摘要
董晓敏,洪海鸥,张洪,徐艳秋,姚蓓,蔡万城.甲状腺及乳腺良性疾病和子宫肌瘤的关联性分析[J].中国临床保健杂志,2019,22(5):627-630.
甲状腺及乳腺良性疾病和子宫肌瘤的关联性分析
Correlation among the prevalence of benign diseases of thyroid,breast and uterine fibroids
投稿时间:2019-03-16  
DOI:10.3969/J.issn.1672-6790.2019.05.014
中文关键词: 平滑肌瘤  甲状腺疾病  乳腺疾病  危险因素  年龄因素
英文关键词: Leiomyoma  Thyroid diseases  Breast diseases  Risk factors  Age factors 〖FL
基金项目:
作者单位E-mail
董晓敏 中国科学技术大学附属第一医院安徽省立医院健康管理中心,合肥 230001] honghaiou@ahtj.com.cn 
洪海鸥 中国科学技术大学附属第一医院安徽省立医院健康管理中心,合肥 230001] honghaiou@ahtj.com.cn 
张洪 中国科学技术大学附属第一医院安徽省立医院健康管理中心,合肥 230001] honghaiou@ahtj.com.cn 
徐艳秋 中国科学技术大学附属第一医院安徽省立医院健康管理中心,合肥 230001] honghaiou@ahtj.com.cn 
姚蓓 中国科学技术大学附属第一医院安徽省立医院健康管理中心,合肥 230001] honghaiou@ahtj.com.cn 
蔡万城 中国科学技术大学附属第一医院安徽省立医院健康管理中心,合肥 230001] honghaiou@ahtj.com.cn 
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中文摘要:
      目的 基于超声检查数据,探讨甲状腺良性疾病、乳腺良性疾病及子宫肌瘤三者之间的关联性。方法 收集2016年1月至2017年1月在安徽省立医院健康管理中心同时进行甲状腺、乳腺彩色多普勒超声及子宫附件超声检查的17 085例女性体检人群资料,对其超声结果进行统计分析。结果 甲状腺良性疾病总患病率54.5%(95% CI: 53.7%~55.2%),随年龄增长,患病率逐渐升高;乳腺良性疾病总患病率52.5%(95%CI :51.7%~53.2%),子宫肌瘤总患病率16.7%(95% CI:15.9%~17.0%),乳腺良性疾病与子宫肌瘤的发病率均呈先升后降的趋势,且都在41-50岁达到最大值。对甲状腺、乳腺良性疾病及子宫肌瘤三者的发病情况进行关联性分析可知:在总人群(控制年龄这一混淆因素)中,每两种疾病的发病情况都显示显著正相关性。按年龄分层之后,得出甲状腺良性疾病与乳腺良性疾病在31~40岁组(P<0.001)、41~50岁组(P=0.008)、61~70岁组(P=0.039),乳腺良性疾病与子宫肌瘤在31~40岁组(P<0.001)、41~50岁组(P=0.002)、51~60岁组(P<0.001)、61~70岁组(P=0.010),甲状腺良性疾病与子宫肌瘤在41~50岁组(P<0.001)、51~60岁组(P=0.045),都显著正相关。结论 甲状腺良性疾病、乳腺良性疾病及子宫肌瘤的发病情况之间存在关联,尤其是围绝经期女性。
英文摘要:
      Objective To investigate the correlation of prevalences among the benign diseases of thyroid,breast and uterine fibroids based on the sonographic findings.Methods The medical records of 17085 women who received Doppler ultrasound of thyroid,breast and B-scan ultrasonography of uterine appendix at the health center of Anhui Provincial Hospital from January 1,6 to January 1,7 were retrospectively reviewed,and the sonographic findings were analyzed.Results The prevalence of benign thyroid diseases was 54.5% (95 CI:53.7%-55.2%),which increased with age;the overall prevalence of benign breast diseases and uterine fibroids were 52.5% (95% CI:51.7%-53.2%) and 16.7% (95% CI:15.9%-17.0%) respectively,each increasing to the highest in 41-50 yr and then beginning to decrease.correlation analysis among the prevalence of thyroid,breast benign diseases and uterine fibroids showed that:(1)Overall,significant positive correlation was observed between each two diseases when considering no age.(2)When stratified by age,benign thyroid disease and benign breast disease were positively correlated in the age groups of 31-40 yr (P<0.001),41-50 yr (P=0.008) and 61-70 yr (P=0.039),and benign breast disease and uterine leiomyoma were positively correlated in the age groups of 31-40 yr (P<0.001),41-50 yr(P=0.002),51-60 yr(P<0.001) and 61-70 yr (P=0.010),and benign thyroid disease and uterine fibroids were positively correlated in the age groups of 41-50 yr (P<0.001) and 51-60 yr(P=0.045).Conclusions There are positive correlations among the prevalences of benign thyroid disease,benign breast disease and uterine fibroids,especially in perimenopause women.
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