文章摘要
戚洪阳,程祖胜.单相抑郁症患者各脑叶CT值的改变与分析[J].中国临床保健杂志,2018,21(6):822-824.
单相抑郁症患者各脑叶CT值的改变与分析
Change and analysis of CT values in each lobe of patients with unipolar depression
投稿时间:2018-08-15  
DOI:10.3969/J.issn.1672-6790.2018.06.026
中文关键词: 抑郁症  中枢神经系统    体层摄影术,X线计算机
英文关键词: Depressive disorder  Central nervous system  Brain  Tomography,X-Ray computed 〖FL
基金项目:浙江省绍兴市卫生计生科技计划项目(2017QN010)
作者单位E-mail
戚洪阳 浙江绍兴市第七人民医院放射科,绍兴 312000 425682298@qq.com 
程祖胜 浙江绍兴市第七人民医院放射科,绍兴 312000  
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中文摘要:
      目的 探讨分析单相抑郁症患者各脑叶CT值的改变情况及与病程的关系。方法 选取我院收治的不同病程单相抑郁症患者50例为观察组,同时选取同期行健康体检者50例为对照组。两组均行颅脑CT扫描,对各脑叶CT值进行比较。结果 观察组患者左额叶CT值、左、右颞叶CT值均明显低于对照组(P<0.05);两组右额叶CT值比较差异无统计学意义(P>0.05);且观察组患者各脑叶CT值比较,右颞叶明显高于其他脑叶(P<0.05);线性回归分析显示单相抑郁症患者左额叶、左颞叶CT值与年龄呈负相关(P<0.05),左额叶CT值与病程呈负相关(P<0.05)。结论 单相抑郁症患者左额叶、左颞叶可见明显萎缩现象,且左额叶萎缩程度多与病程有密切关联,提示该病可能为中枢神经系统退行性疾病。
英文摘要:
      Objective To investigate the relationship between the changes of CT values of cerebral lobes and the course of disease in patients with unipolar depression.Methods A total of 50 cases of unipolar depression with different course were selected as the observation group,and 50 cases of normal people who underwent physical examination at the same time were selected as the control group.Results The CT values of left frontal lobe,left temporal lobe and right temporal lobe in the observation group were significantly lower than those in the control group(P<0.05),and there was no significant difference between the two groups(P>0.05),and the CT values of the right temporal lobe in the monophasic depression group were significantly higher than those in other lobes(P<0.05).The linear regression analysis showed that the CT value of left frontal lobe and left temporal lobe were negatively correlated with age (P<0.05),also the CT value of right frontal lobe was negatively correlated with course of disease (P<0.05).ConclusionThe atrophy of left frontal lobe and temporal lobe can be seen in patients with unipolar depression,and the degree of atrophy of left frontal lobe is closely related to the course of disease.
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