文章摘要
齐馨馨,雷明,李芳,胡泽昆,姚明.阿司匹林预防脑血管病患者早期急性呼吸窘迫综合征的效果[J].中国临床保健杂志,2018,21(5):626-628.
阿司匹林预防脑血管病患者早期急性呼吸窘迫综合征的效果
Clinical study of aspirin on the ARDS in patients with acute cerebrovascular disease of early development
投稿时间:2018-06-22  
DOI:10.3969/J.issn.1672-6790.2018.05.015
中文关键词: 脑血管障碍  呼吸窘迫综合征,成人  阿司匹林  预防
英文关键词: Cerebrovascular disorders  Respiratory distress syndrome,adult  Aspirin  Prevention 〖FL
基金项目:国家交通运输部长江航务管理局重点科技项目(20171001)
作者单位E-mail
齐馨馨 湖北武汉市普仁医院重症医学科,430081 578207332@qq.com 
雷明 武汉长江航运总医院神经内科  
李芳 湖北武汉市普仁医院重症医学科,430081  
胡泽昆 湖北武汉市普仁医院重症医学科,430081  
姚明 湖北武汉市普仁医院重症医学科,430081  
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中文摘要:
      目的 探讨阿司匹林对急性脑血管病早期发生急性呼吸窘迫综合征(ARDS)的预防作用。方法选取64例急性脑血管病患者按照随机数字表法分为观察组(n=32)和对照组(n=32)。对照组给予常规治疗,观察组在对照组的基础上规律服用阿司匹林。观察两组患者住院早期(<7 d)ARDS的发生率,以及两组患者住院期间机械通气时间、重症加强护理病房(ICU)住院时间以及医疗费用。结果 住院早期(<7 d),观察组ARDS的发生率为9.38%(3/32),明显少于对照组的31.25%(10/32),差异有统计学意义(P<0.05);观察组患者机械通气时间、ICU住院时间以及医疗费用明显小于对照组患者,差异具有统计学意义(P<0.05)。结论 阿司匹林治疗能减少急性脑血管病患者早期ARDS的发生率,并有效降低患者机械通气时间、ICU住院时间以及医疗费用。
英文摘要:
      Objective To investigate the preventive effect of aspirin on acute respiratory distress syndrom (ARDS) in patients with acute cerebrovascular disease. Methods A total of 64 patients with acute severe cerebrovascular disease complicated by ARDS were selected.According to the randomized table method,patients were randomly divided into observation group(n=32) and control group (n=32).The control group received routine treatment,and the observation group regularly took aspirin on the basis of the control group.The incidence of early-stage (<7 d) ARDS in the two groups was observed,as well as the duration of mechanical ventilation during hospitalization,the length of hospital stay in the Intensive Care Unit (ICU),and medical expenses. Results In the early stage of hospitalization (<7 d),the incidence of ARDS in the observation group was 9.38% (3/32),which was significantly lower than that in the control group[31.25%(10/32)].The difference was statistically significant (P<0.05).Ventilation time,ICU hospitalization time and medical expenses were significantly lower than those of control group,the difference was statistically significant,P<0.05. Conclusion Aspirin treatment can reduce the incidence of early ARDS in patients with acute cerebrovascular disease,and reduce effectively the mechanical ventilation time,ICU hospitalization time and medical expenses.
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